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International Journal of Biomedical Imaging
Volume 2012, Article ID 940585, 26 pages
Review Article

A Review of Indocyanine Green Fluorescent Imaging in Surgery

1Department of Electrical Engineering and Energy Technology, University of Vaasa, Vaasa, Finland
2Department of Hand Surgery, Tampere University Hospital, 33680 Tampere, Finland
3Department of Neurosurgery, Helsinki University Central Hospital (HUCH), Helsinki, Finland
4Department of Cardiosurgery, Helsinki University Central Hospital, Helsinki, Finland
5Department of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland
6Saratov State University, Saratov 410012, Russia
7Institute of Precise Mechanics and Control, Russian Academy of Sciences, Saratov 410028, Russia
8University of Oulu, Oulu, Finland
9Clinic of Angiosurgery, Helsinki University Central Hospital, Helsinki, Finland

Received 1 September 2011; Accepted 1 February 2012

Academic Editor: Guowei Wei

Copyright © 2012 Jarmo T. Alander et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The purpose of this paper is to give an overview of the recent surgical intraoperational applications of indocyanine green fluorescence imaging methods, the basics of the technology, and instrumentation used. Well over 200 papers describing this technique in clinical setting are reviewed. In addition to the surgical applications, other recent medical applications of ICG are briefly examined.