International Journal of Biomedical Imaging / 2014 / Article / Fig 3

Research Article

Detection of Melanoma Metastases in Resected Human Lymph Nodes by Noninvasive Multispectral Photoacoustic Imaging

Figure 3

Images of two human nodes. The first row shows images of a metastatic node (node number 2 from Table 1); the second row shows images of a benign node (node number 3 from Table 1). Three columns represent, respectively, high-resolution ultrasound, photoacoustic signal, and the calculated resemblance. The third row shows the pathology slides of the metastatic node (g) and the normal node (h). Absence of photoacoustic signal deeper in the malignant node (as indicated by in (b)) seems to be caused by the strong absorption by the melanin in the superficial area of the node. The green area in (c) corresponds to the superficial layer of the dark area in (g). The red structure in (f) corresponds to the vessels in the hilum of the benign lymph node (h).

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