Research Article

A Biomimetic Approach for the Creation of Two-Dimensional Microscale Surface Patterns: Creation of Isolated Immunological Synapses

Figure 2

Fluorescent micrographs demonstrating conjugation of coupling molecules to patterned surfaces. Panels are described in detail in the text; briefly functionalization with (a) aldehyde groups, (b) sulfhydryl groups, (c) biotin molecules, and ((d) and (e)) proteins are illustrated. The patterned squares in all micrographs are ā€‰ m2 and the white scale bars represent 10ā€‰ m.
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(a)
821308.fig.002b
(b)
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(c)
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(d)
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(e)