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International Journal of Biomaterials
Volume 2011, Article ID 129727, 9 pages
Research Article

Biphasic Calcium Phosphate Bioceramics for Orthopaedic Reconstructions: Clinical Outcomes

1Department of Orthopaedic Surgery, Hospital São Bento Cardioclinica Ltda., Rua Crucis 50, 30.360-290 Belo Horizonte, Minas Gerais, Brazil
2Department of Orthopedic Surgery, Federal University of São Paulo, Rua Borges Lagoa 783, 04038-032 São Paulo, Brazil
3Department of Morphology, Federal University of São Paulo, Rua Botucatu 740, 04023-900 São Paulo, Brazil
4Department of Biomaterials and Biomimetics, New York University College of Dentistry, 345 East 24th Street, New York, NY 10010, USA

Received 15 January 2011; Accepted 20 April 2011

Academic Editor: Joo L. Ong

Copyright © 2011 Carlos A. Garrido et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


BCP are considered the most promising biomaterials for bone reconstruction. This study aims at analyzing the outcomes of patients who received BCP as bone substitutes in orthopaedic surgeries. Sixty-six patients were categorized according to the etiology and morphology of the bone defects and received scores after clinical and radiographic evaluations. The final results corresponded to the combination of both parameters and varied from 5 (excellent result) to 2 or lower (poor result). Most of the patients who presented cavitary defects or bone losses due to prosthesis placement or revision, osteotomies, or arthrodesis showed good results, and some of them excellent results. However, patients with segmental defects equal or larger than 3 cm in length were classified as moderate results. This study established clinical parameters where the BCP alone can successfully support the osteogenic process and where the association with other tissue engineering strategies may be considered.