Research Article
Determination of Oxidative Stress Related Toxicity on Repeated Dermal Exposure of Hydroxyapatite Nanoparticles in Rats
Table 2
Haematological values of rats when exposed to HANPs (mean ± SD,
).
| Parameters | Control | HANPs | (25 mg/kg) | (50 mg/kg) | (100 mg/kg) |
| WBC | 5.64 ± 2.20 | 6.25 ± 1.51 | 5.85 ± 1.46 | 7.62 ± 2.22 | RBC | 6.09 ± 0.39 | 6.35 ± 0.48 | 6.14 ± 0.63 | 6.02 ± 0.63 | Hb | 15.77 ± 0.81 | 15.95 ± 0.92 | 15.46 ± 0.10 | 14.66 ± 0.91 | Hct | 33.03 ± 1.82 | 34.58 ± 2.83 | 33.31 ± 3.18 | 32.12 ± 3.20 | PLT | 705.0 ± 106.66 | 702.7 ± 54.49 | 690.1 ± 85.74 | 600.9 ± 71.45 | MCV | 54.5 ± 1.35 | 54.5 ± 1.08 | 54.4 ± 1.51 | 53.5 ± 0.71 | MCH | 25.91 ± 0.92 | 25.14 ± 0.76 | 25.3 ± 1.46 | 24.52 ± 1.33 | MCHC | 47.75* ± 1.39 | 46.2 ± 1.57 | 46.55 ± 2.17 | 45.89 ± 2.42 |
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Statistically significant ; HANPs: hydroxyapatite nanoparticles.
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