Research Article

Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin

Figure 9

In vitro cytotoxicity effect of ivermectin formulated in liposomes (closed circles) on BHK cells. For comparison the same experiments were performed using empty liposomal formulations (open circles). The following liposomal formulations were tested: #PC9-Ch1 and #PC9-Ch1-ive1.0 (a), #PC9-Br1 and #PC9-Br1-ive1.0 (b), #PC9-Br0.5 and #PC9-Br0.5-ive1.0 (c), and #PC18-Br1 and #PC18-Br1-ive1.0 (d). The phosphatidylcholine concentration (top -axis) is related to empty liposomes while the ivermectin concentration (bottom -axis) is related to ivermectin liposomes. Details on the identification codes and liposomal compositions are included in Table 1. Data represent the average of 2 determinations.
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