Research Article

The N-Terminal Domain of Y-Box Binding Protein-1 Induces Cell Cycle Arrest in G2/M Phase by Binding to Cyclin D1

Figure 1

Schematic representation of the fusion constructs and the amino acid sequence of truncated YB-1 proteins. (a) Amino acid sequence of the N-terminal region of each of the truncated YB-1 protein. Note an internal deletion in APYB36GFP which removes the alanine-proline sequence (b) Line drawing of each fusion containing antennapedia, YB-1 and GFP and size of E. coli expressed fusion proteins as analyzed by PAGE followed by western blot analysis.
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(a)
243532.fig.001b
(b)