Designing a Long Acting Erythropoietin by Fusing Three Carboxyl-Terminal Peptides of Human Chorionic Gonadotropin Subunit to the N-Terminal and C-Terminal Coding Sequence
Figure 6
The effect of a single IV injection of EPO variants on reticulocyte counts in mice. ICR mice (/group) received a single IV injection/week for three weeks of rHuEPO, Aranesp, or EPO-(CTP)3 (15 mg/kg). Blood samples were collected after 72 h and reticulocytes were counted. Each point represents the group average of reticulocyte (%) ± SE. ***.
