Table 1: Effect of cannabinoids and acute stress on basal 3H-GABA release. Micro dissected EPL was incubated with 0.1 μM 3H-GABA and superfused with Krebs bicarbonate; after 47 min of superfusion a basal release was reached. Basal release is a % of release and was measured as described in methods and is the median with 95% confidence interval of experiments. The abbreviations of the drugs are as described above.

Control0.50 (0.38–0.65)
 : 65

AEA, 10 uM0.41* (0.31–0.53)
 : 34
Win, 1 uM (0.38–0.59)
 : 22
AM281, 10 uM0.35* (0.3–0.47)
 : 10
URB597, 250 uM0.34* (0.31–0.39)
 : 15
AM 404, 20 uM0.37* (0.27–0.42)
 : 16
THL, 0.5 uM0.94* (0.61–1.06)
 : 6
2AG, 10 uM (0.41–0.6)
 : 26
Acute Stress (0.36–0.54)
 : 30