Transplantable Subcutaneous Hepatoma 22a Affects Functional Activity of Resident Tissue Macrophages in Periphery
Figure 4
Morphological and histological parameters of hepatoma 22a growth (a–c). (a) Tumor volume after s.c. inoculation of 105 live hepatoma cells was measured on days of sacrifice; bars represent areas of viable (empty parts of the bar chart) and necrotized (dashed parts of the bar chart) tumor tissue in percent to the whole tumor volume. Areas of viable and necrotic tissues were calculated in histological sections per field of vision, magnification ×200; ten fields of vision were counted for each mice () (b) The mean number of lymphocytes (1), mast cells (2), polymorphonucleus leukocytes (3), and macrophages (4), infiltrating periphery of the tumor (one field of vision from the edge of the tumor), magnification of ×600 per 10 fields of vision () (c) The mean number of mitoses in viable areas of the tumors at magnification ×900 per 10 fields of vision (). All values are the mean ± SEM.
