Review Article

PU.1 and Haematopoietic Cell Fate: Dosage Matters

Figure 1

Schematic showing the changing expression of PU.1 during haematopoiesis. PU.1 levels, where known, are represented by gradient bars. Gradient bars are not drawn to scale. Differentiation pathways are denoted by arrows. Abbreviations: HSC, haematopoietic stem cell; MPP, multipotent progenitor; CMP, common myeloid progenitor; CLP, common lymphoid progenitor; MEP, megakaryocyte-erythroid progenitor; GMP, granulocyte-macrophage progenitor.
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