Research Article

Synergistic Modulation of Cellular Contractility by Mixed Extracellular Matrices

Figure 6

Effect of nonmuscle myosin II inhibition on deadhesion dynamics of MDA-MB-231 cells. MDA-MB-231 cells were incubated with 5  M blebbistatin for 30 mins prior to deadhesion. ((a), (b)) Blebbistatin treatment led to a significant delay in deadhesion dynamics of MDA-MB-231 cells across all the conditions. Differences in and between untreated cells and blebbistatin-treated cells were statistically significant for all the conditions ( ).
471591.fig.006a
(a)
471591.fig.006b
(b)