Research Article

Partitioning and Exocytosis of Secretory Granules during Division of PC12 Cells

Figure 5

Distribution of SGs during late stages of mitosis. Single confocal planes of immunostained PC12 cells in anaphase ((A)-(C1)) and telophase ((D)-(F1)) are shown as indicated. Note that the majority of SGs during anaphase and telophase was found in the cell midzone ((A) and (D), arrows). A pronounced decoration of spindle microtubules ((E1) and (F1), green arrowheads) with SGs ((E2) and (F2), arrows) was frequently observed during these late stages of mitosis. Scale bars ((A), (C), (D), (F)), 5 μm; ((C1), (F1)), 1 μm.
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