Modulation of Vascular Cell Function by Bim Expression
Wild-type and Bim−/− cells morphology. Wild-type and Bim−/− retinal endothelial cells (panel (a)) and pericytes (panel (b)) were cultured on gelatin or uncoated plates, respectively. Cells were photographed using a phase microscope in digital format at low magnification (×40). In panel (c), retinal endothelial cells prepared from wild-type and Bim−/− mice were examined for the expression of PECAM-1 and VE-cadherin FACScan analysis. In panel (d), retinal pericytes from wild-type and Bim−/− mice were examined for the expression of NG2 and PDGFR- by FACScan analysis. The shaded areas show staining in the presence of control IgG.