Expression of Tra2β in Cancer Cells as a Potential Contributory Factor to Neoplasia and Metastasis

Figure 1

Modular structure of the core SR family proteins SRSF1 (also known as ASF/SF2) and SRSF3 (also known as SRp20) and the SR-like protein Tra2β. The RNA recognition motif (RRM) binds to target RNAs, and the RS region is responsible for protein-protein interactions. SRSF1 has a second RRM, annotated ψRRM. SRSF1 and Tra2β have a PP1 docking site.