Clinical Significance of HER-2 Splice Variants in Breast Cancer Progression and Drug Resistance

Figure 3

Patterns of HER-2 in different cancers. Bar chart shows genetic changes in a wide range of different tumours and cancer types, including mutation, deletion, and amplification. Note that amplification is particularly prevalent in invasive carcinoma of the breast. Data was generated using the cBIO Cancer Genomics Portal [14, 15].