Small G Proteins Dexras1 and RHES and Their Role in Pathophysiological Processes

Figure 6

Dexras1 bound to GDP, nNOS, and CAPON can exist together as a ternary complex. NMDA receptors activation leads to S-Nitrosylation of Dexras1. S-Nitrosylation of Dexras1 leads to exchange of GDP with GTP and this active Dexras1-GTP initiates downstream signals.