Review Article

Hyaluronan Synthesis, Catabolism, and Signaling in Neurodegenerative Diseases

Figure 1

Distribution of HA (white) in lumbar spinal cord white matter (WM) and gray matter (GM). A section of a rat spinal cord was labeled with a biotinylated-HA-binding protein then visualized by fluorescence microscopy following staining with fluorescein-labeled streptavidin. Note that HA is diffusely distributed throughout white matter, but is much more dense in gray matter.