Hyaluronan Synthase 3 Null Mice Exhibit Decreased Intestinal Inflammation and Tissue Damage in the DSS-Induced Colitis Model

Figure 6

Histology of rectal sections from DSS-treated mice. (a) Representative rectal images of hematoxylin and eosin stained cross-sections from mice of each genotype sacrificed on the indicated DSS treatment time point at 10x magnification (scale bar = 200 um). Images captured with a Leica digital brightfield microscope and the Leica application software (LAS). (b) Submucosal swelling of the rectal longitudinal folds (dashed line) in the images presented in panel (a) was measured (area m²) using ImageProPlus software. The untreated wild-type rectal section illustrates the region measured (yellow).

(a)

(b)