Table of Contents Author Guidelines Submit a Manuscript
International Journal of Cell Biology
Volume 2017, Article ID 1917239, 12 pages
Research Article

Effect of Antioxidant Water on the Bioactivities of Cells

1Department of Animal Life and Environmental Science, Hankyong National University, Anseong 17579, Republic of Korea
2Institute for Information Technology Convergence, Division of Electrical Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34138, Republic of Korea
3Department of Mechanical Engineering, The State University of New York Korea, Incheon 21985, Republic of Korea

Correspondence should be addressed to GunWoong Bahng; ten.muad@8023gnhabwg

Received 15 May 2017; Accepted 16 July 2017; Published 17 August 2017

Academic Editor: Richard Tucker

Copyright © 2017 Seong Gu Hwang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


It has been reported that water at the interface of a hydrophilic thin film forms an exclusion zone, which has a higher density than ordinary water. A similar phenomenon was observed for a hydrated hydrophilic ceramic powder, and water turns into a three-dimensional cell-like structure composed of high density water and low density water. This structured water appears to have a stimulative effect on plant growth. This report outlines our study of antioxidant properties of this structured water and its effect on cell bioactivities. Culturing media which were prepared utilizing this antioxidant structured water promoted the viability of RAW 264.7 macrophage cells by up to three times. The same tendency was observed for other cells including IEC-6, C2C12, and 3T3-L1. Also, the cytokine expression of the splenocytes taken from a mouse spleen increased in the same manner. The water also appears to suppress the viability of cancer cell, MCF-7. These results strongly suggest that the structured water helps the activities of normal cells while suppressing those of malignant cells.