Engineering of L-Plastin Peptide-Loaded Biodegradable Nanoparticles for Sustained Delivery and Suppression of Osteoclast Function In Vitro

Table 1

Physicochemical characterization of nanoparticles.

Nanoparticles	Size		Zeta potential	Peptide loading (%)
PLGA-PEG_P1	157 ± 4	0.058 ± 0.02	- 3.6 ± 0.8	5
PLGA-PEG_P3	136 ± 5	0.062 ± 0.03	- 3.1 ± 0.2	5

Physicochemical characterization data represents the average of 3 independent experiments ± SD.
Hydrodynamic diameter (number mean) measured by dynamic light scattering.
Polydispersity index (PDI) indicates the distribution of individual molecular masses in a batch of nanoparticles, measured by dynamic light scattering.
Surface charge measured at 25°C in 15x diluted PBS with ~9 mM NaCl, pH 7.4.
Table 1 layout is used from Wadajkar et al., 2017 (ref. [20]) (under the Creative Commons Attribution License/public domain).