International Journal of Cell Biology

Selective Types of Autophagy


Publishing date
15 Apr 2012
Status
Published
Submission deadline
15 Oct 2011

Lead Editor

1Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway

2Department of Cell Biology, Cell Microscopy Centre and Institute of Biomembranes, University Medical Centre Utrecht, Utrecht, The Netherlands

3BioScience Center, San Diego State University, San Diego, CA, USA

4The Tokyo Metropolitan Institute Medical Science, Tokyo, Japan


Selective Types of Autophagy

Description

Macroautophagy, thereafter called autophagy, is a catabolic transport route conserved among eukaryotes by which the cells degrade their own cytoplasmic components into lysosomes/vacuoles. This process occurs at a basal level in most tissues to regulate cell growth and prevent the accumulation of toxic protein aggregates and defective subcellular organelles, but autophagy can also be induced by certain environmental cues or intracellular stress including invading pathogens. During autophagy, cytoplasmic constituents become sequestered into de novo synthesized double-membrane vesicles called autophagosomes, which then fuse with lysosomes/vacuoles. Autophagy was long considered a nonselective bulk process, but it is now evident that specific cargo destined for destruction, including aggregate-prone proteins, dysfunctional organelles, as well as various pathogens, become selectively incorporated into autophagosomes. Such specificity allows for cellular quality control mechanisms, which have been shown to be important in various physiological and pathological situations. Thus, a dissection of the selective types of autophagy at the molecular level and its regulations might lead to identification of targets for future therapeutics.

We invite authors to submit original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular mechanisms underlying the various forms of selective autophagy and their role in development, health, and disease. Papers on the mechanism and regulation of autophagy will also be considered. Potential topics include, but are not limited to:

  • Selective recognition of autophagy cargo
  • Autophagy receptors and adaptor proteins
  • Regulation of selective autophagy
  • Selective autophagy and development
  • Selective autophagy and the immune system
  • The pathophysiology of selective autophagy
  • Generation of conceptual and practical tools to modulate selective autophagy

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijcb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 156272
  • - Editorial

Selective Types of Autophagy

Fulvio Reggiori | Masaaki Komatsu | ... | Anne Simonsen
  • Special Issue
  • - Volume 2012
  • - Article ID 179207
  • - Research Article

WIPI-1 Positive Autophagosome-Like Vesicles Entrap Pathogenic Staphylococcus aureus for Lysosomal Degradation

Mario Mauthe | Wenqi Yu | ... | Tassula Proikas-Cezanne
  • Special Issue
  • - Volume 2012
  • - Article ID 219625
  • - Review Article

Autophagy: More Than a Nonselective Pathway

Fulvio Reggiori | Masaaki Komatsu | ... | Anne Simonsen
  • Special Issue
  • - Volume 2012
  • - Article ID 208014
  • - Research Article

MAP1B Interaction with the FW Domain of the Autophagic Receptor Nbr1 Facilitates Its Association to the Microtubule Network

Katie Marchbank | Sarah Waters | ... | Caroline A. Whitehouse
  • Special Issue
  • - Volume 2012
  • - Article ID 396705
  • - Review Article

Zymophagy: Selective Autophagy of Secretory Granules

Maria I. Vaccaro
  • Special Issue
  • - Volume 2012
  • - Article ID 146767
  • - Review Article

Selective Autophagy in Drosophila

Ioannis P. Nezis
  • Special Issue
  • - Volume 2012
  • - Article ID 431684
  • - Review Article

The Many Faces of Mitochondrial Autophagy: Making Sense of Contrasting Observations in Recent Research

Alexander I. May | Rodney J. Devenish | Mark Prescott
  • Special Issue
  • - Volume 2012
  • - Article ID 872091
  • - Review Article

Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival

Luke R. K. Hughson | Vincent I. Poon | ... | Julian J. Lum
  • Special Issue
  • - Volume 2012
  • - Article ID 282041
  • - Review Article

Lipophagy: Connecting Autophagy and Lipid Metabolism

Rajat Singh | Ana Maria Cuervo
  • Special Issue
  • - Volume 2012
  • - Article ID 189794
  • - Review Article

Alternative Macroautophagic Pathways

Katrin Juenemann | Eric A. Reits
International Journal of Cell Biology
 Journal metrics
Acceptance rate11%
Submission to final decision65 days
Acceptance to publication109 days
CiteScore8.500
Impact Factor-
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