Chitosan-Based Macromolecular Biomaterials for the Regeneration of Chondroskeletal and Nerve Tissue

Table 1

CHI-containing devices used for bone and nerve tissue regeneration in humans.

Device	Tissue	Time	Reference
CHI ascorbate gel	periodontium	2 months	[35]
Me-pyrrolidinone-CHI gel	tooth alveolar bone	6 months	[36]
DCMC-CaP^a gel or solution	mandible bone	15 days	[41]
CHI conduits with PGA^b filaments	right arm median nerve	36 months	[86]

^aN,N-dicarboxymethyl CHI with calcium phosphate;
^bpoly(glycolic acid).