Review Article

Structure and Dynamics of Glycosphingolipids in Lipid Bilayers: Insights from Molecular Dynamics Simulations

Figure 4

Snapshots of binary lipid bilayers composed of DPPC and GM1 in the ratio 94 : 4 (a) or 78 : 20 (b). A decrease in the DPPC : GM1 ratio leads to a broadening of the polar interface and thickening of the bilayer. The snapshots are from the simulations sym94 : 4 (at 14 ns) and sym78 : 20 (also at 14 ns) [28] and are rendered using VMD [35]. Polar atoms of DPPC and head-groups of GM1 are rendered as yellow and blue spheres, respectively. Other carbon atoms of DPPC and GM1 are rendered as green and magenta sticks, respectively.
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(a)
950256.fig.004b
(b)