International Journal of Carbohydrate Chemistry

Chitosan and Chitosan Derivatives for Biological Applications: Chemistry and Functionalization


Publishing date
01 Aug 2011
Status
Published
Submission deadline
01 Feb 2011

Lead Editor

1Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Portugal and Department of Pharmaceutical Sciences, Instituto Superior de Ciências da Saúde–Norte, Gandra, Portugal

2Department of Pharmacy and Pharmaceutical Technology, University of Santiago de Compostela, Santiago de Compostela, Spain

3Department of Pharmaceutical Technology, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

4Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Porto, Porto, Portugal


Chitosan and Chitosan Derivatives for Biological Applications: Chemistry and Functionalization

Description

Chitosan is a polysaccharide with structural characteristics similar to glycosamines, obtained by alkaline deacetylation of chitin, and derived from the exoskeleton of crustaceans. Studies on chitin and chitosan have been performed because these polymers show excellent biological properties such as biodegradation in the human body, and immunological, antibacterial, and wound-healing activity. Moreover, chitosan possesses excellent properties when included into drug delivery systems and once used for tissue engineering applications.

Most of the commercial use of chitin and chitosan has been confined to the unmodified forms. For an advance in its utilization, chemical modification to introduce a variety of functional groups to chitosan has been established, aiming the improvement of its properties.

Chemical modification can be used to attach various functional groups and to control hydrophobic, cationic, and anionic properties. Moreover, chemical modification of chitosan provides derivatives that are soluble at neutral and basic pH. Still, most of the new derivatives are in the beginning of their development, and more fundamental studies on chemical modification are required to attest the safety, security, and efficacy of their use.

We are particularly interested in articles describing the synthesis, characterization, and biological applications of chitosan derivatives. Special importance is expected on the role of individual functional groups in applications of modified chitosan. Potential topics include, but not limited to:

  • Graft copolymerization for chemical modification of chitosan
  • Chitosan derivatives developed to overcome chitosan solubility drawbacks
  • Chitosan derivatives developed to overcome chitosan biocompatibility drawbacks
  • Enzymatic Modifications of chitin and chitosan
  • Chitosan-based systems with temperature-responsive behavior
  • Dietary fiber and alteration of bile composition of chitosan and derivatives
  • Recent advances in drug delivery systems based on chitosan derivatives
  • Recent advances in tissue engineering systems based on chitosan derivatives
  • Chitosan functionalization with cell ligands and antibodies

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijcc/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 802693
  • - Editorial

Chitosan and Chitosan Derivatives for Biological Applications: Chemistry and Functionalization

Bruno Sarmento | Francisco M. Goycoolea | ... | José das Neves
  • Special Issue
  • - Volume 2011
  • - Article ID 865704
  • - Review Article

Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery

Fernanda Andrade | Francisco Goycoolea | ... | Bruno Sarmento
  • Special Issue
  • - Volume 2011
  • - Article ID 809743
  • - Research Article

Consequences of Neutralization on the Proliferation and Cytoskeletal Organization of Chondrocytes on Chitosan-Based Matrices

Sandra E. Noriega | Anuradha Subramanian
  • Special Issue
  • - Volume 2011
  • - Article ID 146419
  • - Research Article

Selective Modification of Chitosan to Enable the Formation of Chitosan-DNA Condensates by Electron Donator Stabilization

Karl E. Kador | Anuradha Subramanian
  • Special Issue
  • - Volume 2011
  • - Article ID 312539
  • - Review Article

Quaternary Salts of Chitosan: History, Antimicrobial Features, and Prospects

Douglas de Britto | Rejane Celi Goy | ... | Odilio B. G. Assis
  • Special Issue
  • - Volume 2011
  • - Article ID 303708
  • - Review Article

Chitosan-Based Macromolecular Biomaterials for the Regeneration of Chondroskeletal and Nerve Tissue

Giulio D. Guerra | Niccoletta Barbani | ... | Caterina Cristallini
  • Special Issue
  • - Volume 2011
  • - Article ID 460381
  • - Review Article

A Biopolymer Chitosan and Its Derivatives as Promising Antimicrobial Agents against Plant Pathogens and Their Applications in Crop Protection

Mohamed E. I. Badawy | Entsar I. Rabea

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.