Does Intensive Glucose Control Prevent Cognitive Decline in Diabetes? A Meta-Analysis

Table 4

Results of weighted SMDs for each cognitive test.

Cognitive test	Number of studies	Weighted SMD (95% CI)	-squared
Type 1 diabetes
DSST	3	0.02 (−0.05 to 0.09)	0%	0.60
Trail Making Test	4	−0.07 (−0.14 to 0.00)	85%	0.05
Similarities subtest of WAIS	3	0.015 (−0.06 to 0.09)	60%	0.69
RAVLT	3	−0.022 (−0.09 to 0.05)	72%	0.56
Finger tap from the dominant hand	4	0.032 (−0.04 to 0.106)	76%	0.39
Finger tap from nondominant hand	4	−0.045 (−0.123 to 0.024)	83%	0.19
Type 2 diabetes
DSST	2	0.71 (0.64 to 0.78)	97%	<0.01
Trail Making Test	2	−0.29 (−0.55 to −0.02)	94%	0.04
RAVLT	2	−0.185 (−0.26 to −0.16)	66%	<0.01
Stroop test	2	−0.79 (−0.87 to −0.72)	97%	<0.01