Review Article

Limitations of Serum Ferritin in Diagnosing Iron Deficiency in Inflammatory Conditions

Table 2

Proposed serum ferritin and TSAT thresholds for the diagnosis of iron deficiency in patients with or without inflammatory conditions.

PopulationThresholds

No inflammatory condition [43]Serum ferritin < 30 μg/L (N.B.: false negatives are common)

Inflammatory conditions [4, 5]Serum ferritin < 100 μg/L or TSAT < 20%
If serum ferritin is 100–300 μg/L, a TSAT test is required to confirm iron deficiency

TSAT, transferrin saturation.