Association of BIRC5 Gene Polymorphism with the Collateral Circulation and Severity of Large Artery Atherosclerotic Stroke

Table 4

Association of BIRC5 SNP of rs2071214 with the collateral circulation of stroke patients.

Variables	Poor group (0–2) n = 250	Good group (3–4) n = 178	^a	OR (95% CI)^a
rs 2071214
Additive model
AA	86 (34.40%)	69 (38.76%)	Ref	1.00
GA	110 (44.00%)	90 (50.56%)	0.685	1.150 (0.585–2.263)
GG	54 (21.60%)	19 (10.68%)	0.007	3.592 (1.410–9.150)
Dominant model
AA	86 (34.40%)	69 (38.76%)	Ref	1.00
GA/GG	164 (65.60%)	109 (61.24%)	0.194	1.526 (0.807–2.886)
Recessive model
AA/GA	196 (78.40%)	159 (89.32%)	Ref	1.00
GG	54 (21.60%)	19 (10.68%)	0.006	3.313 (1.420–7.727)

Logistic regression analysis was used to evaluate the distribution of genotype frequencies of rs2071214 polymorphisms in good collateral circulation and bad collateral circulation group. OR, odds ratio; CI, confidence interval; Ref, reference; SNP, single nucleotide polymorphism.^a Adjusted for age, sex, hypertension, HDL-C, vascular stenosis degree.