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International Journal of Dentistry
Volume 2014 (2014), Article ID 172854, 10 pages
Clinical Study

Alveolar Ridge Preservation Using Xenogeneic Collagen Matrix and Bone Allograft

1Private Practice Limited to Periodontics, 33 Sp. Merkouri Street, 11634 Athens, Greece
2Department of Periodontology, School of Dental Medicine, Tufts University, Boston, MA, USA
3Division of Periodontology, College of Dentistry, The Ohio State University, Columbus, OH, USA
4Department of Oral Pathology and Medicine, University of Athens, Athens, Greece

Received 3 July 2014; Revised 25 August 2014; Accepted 1 September 2014; Published 24 September 2014

Academic Editor: Gilberto Sammartino

Copyright © 2014 Andreas O. Parashis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Alveolar ridge preservation (ARP) has been shown to prevent postextraction bone loss. The aim of this report is to highlight the clinical, radiographic, and histological outcomes following use of a bilayer xenogeneic collagen matrix (XCM) in combination with freeze-dried bone allograft (FDBA) for ARP. Nine patients were treated after extraction of 18 teeth. Following minimal flap elevation and atraumatic extraction, sockets were filled with FDBA. The XCM was adapted to cover the defect and 2-3 mm of adjacent bone and flaps were repositioned. Healing was uneventful in all cases, the XCM remained in place, and any matrix exposure was devoid of further complications. Exposed matrix portions were slowly vascularized and replaced by mature keratinized tissue within 2-3 months. Radiographic and clinical assessment indicated adequate volume of bone for implant placement, with all planned implants placed in acceptable positions. When fixed partial dentures were placed, restorations fulfilled aesthetic demands without requiring further augmentation procedures. Histological and immunohistochemical analysis from 9 sites (4 patients) indicated normal mucosa with complete incorporation of the matrix and absence of inflammatory response. The XCM + FDBA combination resulted in minimal complications and desirable soft and hard tissue therapeutic outcomes, suggesting the feasibility of this approach for ARP.