Amoxicillin/Clavulanic Acid for the Treatment of Odontogenic Infections: A Randomised Study Comparing Efficacy and Tolerability versus Clindamycin

Table 4

Summary of commonly observed treatment emergent AEs (≥3% in either of the arms).

MedDRA preferred term	Amoxicillin/clavulanic acid; ()	Clindamycin; ()
Total number of treatment emergent AEs	243	236
Subjects who experienced at least one AE	123 (52.1%)	124 (52.8%)
Abdominal discomfort	11 (4.7%)	7 (3.0%)
Alanine aminotransferase increased	26 (11.0%)	24 (10.2%)
Aspartate aminotransferase increased	24 (10.2%)	20 (8.5%)
Blood bilirubin increased	12 (5.1%)	13 (5.5%)
Diarrhoea	19 (8.1%)	28 (11.9%)
Dizziness	18 (7.6%)	14 (6.0%)
Headache	8 (3.4%)	14 (6.0%)
Increased appetite	20 (8.5%)	15 (6.4%)
Nausea	7 (3.0%)	4 (1.7%)
Somnolence	19 (8.1%)	17 (7.2%)