Research Article
Demineralized Freeze-Dried Bovine Cortical Bone: Its Potential for Guided Bone Regeneration Membrane
Table 1
Grading scale for tissue response analysis of the membrane [
7].
| Reaction zone | Response | Score |
| Capsule quantitatively | Thickness rating: | | (i) l–4 fibroblasts | 4 | (ii) 5–9 fibroblasts | 3 | (iii) 10–30 fibroblasts | 2 | (iv) >30 fibroblasts | 1 | (v) Not applicable | 0 |
| Capsule qualitatively | (i) Capsule tissue is fibrous, mature, not dense, resembling connective or fat tissue in the noninjured regions | 4 | (ii) Capsule tissue is fibrous but immature, showing fibroblasts and little collagen | 3 | (iii) Capsule tissue is granulous and dense, containing both fibroblasts and many inflammatory cells | 2 | (iv) Capsule consists of masses of inflammatory cells with little or no signs of connective tissue organization | 1 | (v) Cannot be evaluated because of infection or other factors not necessarily related to the material | 0 |
| Interface qualitatively | (i) Fibroblasts contact the implant surface without the presence of macrophages or foreign body giant cells | 4 | (ii) Scattered foci of macrophages and foreign body cells are present | 3 | (iii) One layer of macrophages and foreign body cells is present | 2 | (iv) Multiple layers of macrophages and foreign body cells are present | 1 | (v) Cannot be evaluated because of infection or other factors not necessarily related to the material | 0 |
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