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International Journal of Dentistry
Volume 2017 (2017), Article ID 6185395, 6 pages
https://doi.org/10.1155/2017/6185395
Research Article

The Effect of Fermented Lingonberry Juice on Candida glabrata Intracellular Protein Expression

1Department of Oral and Maxillofacial Diseases, Helsinki University Hospital (HUH), University of Helsinki, Haartmaninkatu 8, Box 63, 00014 Helsinki, Finland
2Department of Biosciences, Division of Biochemistry and Biotechnology, University of Helsinki, Viikinkaari 5D, 00790 Helsinki, Finland
3Division of Periodontology, Department of Dental Medicine, Karolinska Institutet, Box 4064, 141 04 Huddinge, Sweden

Correspondence should be addressed to Pirjo Pärnänen

Received 8 January 2017; Accepted 28 February 2017; Published 30 March 2017

Academic Editor: Vincent Everts

Copyright © 2017 Pirjo Pärnänen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. L. Fidel Jr., J. A. Vazquez, and J. D. Sobel, “Candida glabrata: review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans,” Clinical Microbiology Reviews, vol. 12, no. 1, pp. 80–96, 1999. View at Google Scholar · View at Scopus
  2. C.-Y. Low and C. Rotstein, “Emerging fungal infections in immunocompromised patients,” F1000 Medicine Reports, vol. 3, no. 1, article 14, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. J.-P. Vermitsky and T. D. Edlind, “Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor,” Antimicrobial Agents and Chemotherapy, vol. 48, no. 10, pp. 3773–3781, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. C. J. Seneviratne, Y. Wang, L. Jin, Y. Abiko, and L. P. Samaranayake, “Proteomics of drug resistance in Candida glabrata biofilms,” Proteomics, vol. 10, no. 7, pp. 1444–1454, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Nawaz, P. Pärnänen, K. Kari, and J. H. Meurman, “Proteolytic activity and cytokine up-regulation by non-albicans Candida albicans,” Archives of Microbiology, vol. 197, no. 4, pp. 533–537, 2015. View at Publisher · View at Google Scholar · View at Scopus
  6. P. Pärnänen, J. H. Meurman, and T. Sorsa, “The effects of Candida proteinases on human proMMP-9, TIMP-1 and TIMP-2,” Mycoses, vol. 54, no. 4, pp. 325–330, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. P. Pärnänen, J. H. Meurman, and P. Nikula-Ijäs, “A novel Candida glabrata cell wall associated serine protease,” Biochemical and Biophysical Research Communications, vol. 457, no. 4, pp. 676–680, 2015. View at Publisher · View at Google Scholar · View at Scopus
  8. R. Puupponen-Pimiä, L. Nohynek, H.-L. Alakomi, and K.-M. Oksman-Caldentey, “Bioactive berry compounds—novel tools against human pathogens,” Applied Microbiology and Biotechnology, vol. 67, no. 1, pp. 8–18, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. R. Puupponen-Pimiä, L. Nohynek, H.-L. Alakomi, and K.-M. Oksman-Caldentey, “The action of berry phenolics against human intestinal pathogens,” BioFactors, vol. 23, no. 4, pp. 243–251, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. L. J. Nohynek, H.-L. Alakomi, M. P. Kähkönen et al., “Berry phenolics: antimicrobial properties and mechanisms of action against severe human pathogens,” Nutrition and Cancer, vol. 54, no. 1, pp. 18–32, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Pärnänen, “A preparation for balancing the oral microbial flora,” EPO 11795242.4.
  12. A. Ullah, M. I. Lopes, S. Brul, and G. J. Smits, “Intracellular pH homeostasis in Candida glabrata in infection-associated conditions,” Microbiology, vol. 159, no. 4, pp. 803–813, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. M. L. Delgado, J. E. O'Connor, I. Azorín, J. Renau-Piqueras, M. L. Gil, and D. Gozalbo, “The glyceraldehyde-3-phosphate dehydrogenase polypeptides encoded by the Saccharomyces cerevisiae TDH1, TDH2 and TDH3 genes are also cell wall proteins,” Microbiology, vol. 147, no. 2, pp. 411–417, 2001. View at Publisher · View at Google Scholar · View at Scopus
  14. C. V. Loureiro y Penha, P. H. B. Kubitschek, G. Larcher et al., “Proteomic analysis of cytosolic proteins associated with petite mutations in Candida glabrata,” Brazilian Journal of Medical and Biological Research, vol. 43, no. 12, pp. 1203–1214, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Tükenmez, H. M. Magnussen, M. Kovermann, A. Byström, M. Wolf-Watz, and B. G. Vertessy, “Linkage between fitness of yeast cells and adenylate kinase catalysis,” PLoS ONE, vol. 11, no. 9, Article ID e0163115, 2016. View at Publisher · View at Google Scholar
  16. J. Ahn, M. Won, J.-H. Choi et al., “Small heat-shock protein Hsp9 has dual functions in stress adaptation and stress-induced G2-M checkpoint regulation via Cdc25 inactivation in Schizosaccharomyces pombe,” Biochemical and Biophysical Research Communications, vol. 417, no. 1, pp. 613–618, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. H. Kusch, S. Engelmann, D. Albrecht, J. Morschhäuser, and M. Hecker, “Proteomic analysis of the oxidative stress response in Candida albicans,” Proteomics, vol. 7, no. 5, pp. 686–697, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. C. J. Seneviratne, Y. Wang, L. Jin, Y. Abiko, and L. P. Samaranayake, “Candida albicans biofilm formation is associated with increased anti-oxidative capacities,” Proteomics, vol. 8, no. 14, pp. 2936–2947, 2008. View at Publisher · View at Google Scholar · View at Scopus