Lymphangiogenesis in Oral Squamous Cell Carcinoma: Correlation with VEGF-C Expression and Lymph Node Metastasis

Table 3

Assessment of LV density, surface area, and roundness.

	Normal; mucosa (n = 6)		Positive LN; OSCC (n = 30)		Negative LN; OSCC (n = 30)		p value	Between normal and positive LN OSCC		Between normal and negative LN OSCC		Between positive and negative LN OSCC
	Mean	SD	Mean	SD	Mean	SD		95% CI	SE	95% CI	SE	95% CI	SE
(I) LVD	5.5	0.58	6.88	0.95	8.33	0.76	0.0001	−2.20 to −0.56	0.4	−3.5 to −2.16	0.33	−1.89 to; −1.01	0.22
(II) LV area (μm^2)	242723	81526	337929	97914	289621	59013	0.045	−182164.66 to −8247.34	42789.49	−104002.39 to 10206.39	28099.19	6527.4 to 90088.6	20872.38
(III) LV roundness	2	0.4	1.8	0.5	2.1	0.6	0.026	−0.24 to 0.64	0.22	−0.623 to 0.423	0.26	−0.59 to −0.02	0.14