β₂-Microglobulin and Neutrophil Gelatinase-Associated Lipocalin, Potential Novel Urine Biomarkers in Periodontitis: A Cross-Sectional Study in Japanese

Table 6

Multivariate regression analysis of the associations between NGAL and variables.

	Standardized β	t	P value
Age (years)	0.154	1.550	0.124
Smoking status (pack-years)	−0.084	−0.859	0.393
BMI	−0.109	−1.020	0.310
eGFR (ml/min/1.73 m^2)	0.008	0.073	0.942
HbA1C (%)	−0.057	−0.550	0.583
Hs-CRP	−0.134	−1.355	0.178
BOP (%)	−0.184	−1.571	0.119
P. gingivalis in subgingival plaque (copy)	0.008	0.067	0.947
CAL ≥ 6 mm (number of sites)	0.260	2.206	0.030

Multivariate regression analysis was performed by the force entry model. Age, smoking status, BMI, eGFR, HbA1C, hs-CRP, BOP, copy number of P. gingivalis in the subgingival plaque, and the number of sites with CAL ≥ 6 mm were used as variables. To obtain the normal distribution, the values of P. gingivalis in the subgingival plaque were used after logarithmic conversion. hs-CRP and the number of sites with CAL ≥ 6 mm were converted to an ordinal value as described in Materials and Methods. R = 0.391; adjusted R² = 0.074. Values statistically significant at .