Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains
Table 2
Comparison of the antimicrobial activity of tumbo dentifrice against seven strains of the oral cavity (formulation without fluoride).
Microorganisms
Part of the plant
Evaluation time (hours)
Mean ± SD
Min
Max
S. mutans
Pulp
24
20.0 ± 2.1
17.8
25.2
0.093
48
19.3 ± 1.1
17.6
21.1
0.479
Peel
24
16.0 ± 1.5
14.6
18.6
0.008
48
15.5 ± 1.5
13.8
18.0
0.061
E. faecalis
Pulp
24
15.5 ± 1.1
13.8
17.3
0.492
48
15.2 ± 1.2
13.0
17.0
0.999
Peel
24
15.5 ± 0.4
15.0
16.5
0.647
48
15 ± 0.4
14.3
15.8
0.988
Actinomyces
Pulp
24
18.3 ± 1
17.3
20.2
0.012
48
23.6 ± 4.4
17.0
29.0
0.078
Peel
24
18.7 ± 3.3
16.3
29.1
48
18.6 ± 3.3
16.3
29.1
Lactobacillus
Pulp
24
20.8 ± 0.6
19.8
22.1
0.623
48
20.2 ± 0.7
18.9
21.5
0.491
Peel
24
17.6 ± 0.2
17.2
18.1
0.842
48
17.1 ± 0.2
16.8
17.6
0.511
C. albicans
Pulp
24
15.5 ± 0.9
13.8
17.1
0.730
48
24.7 ± 1.3
23.0
27.2
0.540
Peel
24
19.3 ± 1.7
16.2
22.3
0.534
48
18.8 ± 1.8
16.0
22.1
0.274
S. sanguinis
Pulp
24
14.9 ± 0.1
14.7
15.3
0.331
48
14.1 ± 0.5
12.9
14.9
0.555
Peel
24
15.9 ± 0.4
15.3
16.6
0.447
48
15.1 ± 0.5
14.2
16.0
0.406
S. oralis
Pulp
24
14.5 ± 0.9
13.6
16.4
0.016
48
14.1 ± 0.9
13.0
16.2
0.195
Peel
24
16.5 ± 0.4
15.6
17.3
0.699
48
15.7 ± 0.6
14.8
16.8
0.941
All measurements were made in mm. Shapiro–Wilk test.
