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Research Article

Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains

Table 3

Comparison of the antimicrobial activity of tumbo dentifrice against seven strains of the oral cavity (formulation with fluoride).


Microorganisms	Part of the plant	Evaluation time (hours)	Mean ± SD	Min	Max

S. mutans	Pulp	24	21.0 ± 1.8	19.2	25.6	0.029
	Pulp	48	19.8 ± 1.4	17.9	22.3	0.178
	Peel	24	14.9 ± 0.4	13.8	15.5	0.070
	Peel	48	14.5 ± 0.4	13.5	15.2	0.178

E. faecalis	Pulp	24	16.3 ± 3.9	12.9	25.3
	Pulp	48	13.8 ± 1.4	11.3	15.8	0.442
	Peel	24	14.3 ± 0.3	13.8	14.9	0.205
	Peel	48	13.9 ± 0.5	12.8	14.8	0.754

Actinomyces	Pulp	24	19.0 ± 0.8	17.8	20.2	0.838
	Pulp	48	22.1 ± 1.3	19.9	24.6	0.717
	Peel	24	18.9 ± 3.2	17.2	29.2
	Peel	48	18.9 ± 3.2	17.2	29.2

Lactobacillus	Pulp	24	21.0 ± 0.3	20.6	21.9	0.268
	Pulp	48	20.3 ± 0.5	19.6	21.2	0.795
	Peel	24	18.1 ± 0.4	17.5	18.9	0.704
	Peel	48	17.5 ± 0.4	16.8	18.2	0.765

C. albicans	Pulp	24	17.4 ± 1.4	15.7	19.7	0.155
	Pulp	48	21.2 ± 1.9	17.0	23.6	0.180
	Peel	24	21.1 ± 0.9	20.2	22.6	0.064
	Peel	48	19.4 ± 3.1	9.8	22.0

S. sanguinis	Pulp	24	15.3 ± 0.3	15.0	16.0	0.205
	Pulp	48	14.0 ± 0.3	13.7	14.9	0.057
	Peel	24	15.5 ± 0.5	14.9	16.5	0.084
	Peel	48	14.8 ± 0.5	14.0	16.2	0.126

S. oralis	Pulp	24	14.4 ± 0.4	13.6	15.0	0.625
	Pulp	48	14.3 ± 0.7	12.9	15.5	0.932
	Peel	24	17.0 ± 0.4	16.5	17.7	0.165
	Peel	48	16.4 ± 0.5	15.6	17.0	0.029

All measurements were made in mm. Shapiro–Wilk test.