Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains
Table 4
Comparison of the antimicrobial activity of tumbo dentifrice against different commercial toothpastes.
Microorganisms
Groups
Mean ± SD
Min
Max
S. mutans
Pulp
20.0 ± 2.1
17.8
25.2
0.093
0.651++
Peel
16.0 ± 1.5
14.6
18.6
0.008
Dento Herbal®
17.0 ± 0.6
16.2
17.8
0.734
Colgate Herbal®
16.9 ± 0.8
16.1
17.8
0.386
Kolynos Herbal®
15.1 ± 0.2
14.9
15.5
0.392
Sensodyne®
11.2 ± 0.8
10.0
12.0
0.191
Parodontax®
30.2 ± 1.5
28.9
32.5
0.194
E. faecalis
Pulp
15.5 ± 1.1
13.8
17.3
0.492
0.906+
Peel
15.5 ± 0.4
15.0
16.5
0.647
Dento Herbal®
12.8 ± 0.4
12.3
13.2
0.303
Colgate Herbal®
13.9 ± 0.8
12.9
14.9
0.900
Kolynos Herbal®
14.2 ± 0.6
13.5
14.9
0.513
Sensodyne®
10.6 ± 0.3
10.2
11.0
0.408
Parodontax®
15.7 ± 0.2
15.5
16.1
0.649
Actinomyces
Pulp
18.3 ± 1
17.3
20.2
0.012
0.143++
Peel
18.7 ± 3.3
16.3
29.1
0.000
Dento Herbal®
14.1 ± 0.4
13.8
14.7
0.303
Colgate Herbal®
15 ± 0.1
14.8
15.2
0.714
Kolynos Herbal®
13.4 ± 0.1
13.2
13.6
0.000
Sensodyne®
13.2 ± 0.2
12.9
13.5
0.000
Parodontax®
14.1 ± 0.5
13.5
14.9
0.889
Lactobacillus
Pulp
20.8 ± 0.6
19.8
22.1
0.623
Peel
17.6 ± 0.2
17.2
18.1
0.842
Dento Herbal®
17.7 ± 0.6
17.0
18.3
0.443
Colgate Herbal®
21.2 ± 0.9
20.1
22.3
0.997
Kolynos Herbal®
22.1 ± 0.8
20.9
23.0
0.696
Sensodyne®
15.5 ± 2.8
12.9
18.3
0.126
Parodontax®
15.2 ± 0.2
14.9
15.5
0.910
C. albicans
Pulp
17.4 ± 1.4
15.7
19.7
0.730
Peel
21.1 ± 0.9
20.2
22.6
0.534
Dento Herbal®
17.9 ± 0.6
17.3
18.7
0.513
Colgate Herbal®
21.7 ± 0.4
21.2
22.3
0.970
Kolynos Herbal®
20.9 ± 1.5
19.9
23.2
0.025
Sensodyne®
0
0
0
—
Parodontax®
24.4 ± 0.6
23.8
25.0
0.111
S. sanguinis
Pulp
14.9 ± 0.1
14.7
15.3
0.331
1.000+
Peel
15.9 ± 0.4
15.3
16.6
0.447
Dento Herbal®
19.7 ± 0.5
19.0
20.2
0.369
Colgate Herbal®
21.1 ± 0.5
20.4
21.8
0.994
Kolynos Herbal®
20.4 ± 1.1
19.6
22.1
0.211
Sensodyne®
0
0
0
—
Parodontax®
26.1 ± 0.5
25.6
26.9
0.680
S. oralis
Pulp
14.5 ± 0.9
13.6
16.4
0.016
0.425++
Peel
16.5 ± 0.4
15.6
17.3
0.699
Dento Herbal®
16 ± 0.6
15.2
16.8
0.999
Colgate Herbal®
15.6 ± 0.5
15.1
16.3
0.688
Kolynos Herbal®
19.9 ± 0.1
19.8
20.2
0.849
Sensodyne®
0
0
0
—
Parodontax®
17.7 ± 0.4
17.2
18.2
0.420
All measurements were made in mm. The concentrations were calculated from the dilutions of the active ingredient; the Sensodyne control group was excluded from any statistical analysis because the antimicrobial activity was not present. Shapiro–Wilk test. +Student t-test. ++Mann–Whitney U test. ANOVA test. †Kruskal–Wallis test. Level of significance .
