Oral Cancer and Oral Potentially Malignant Disorders
1School of Dentistry, The University of Queensland, Brisbane, QLD, Australia; Oral Oncology Research Program, UQ Centre for Clinical Research, Royal Brisbane & Women's Hospital, Herston, Brisbane, QLD, Australia
2The University of Chicago, Chicago, IL, USA
3Faculty of Dentistry, The University of Malaya, Kuala Lumpur, Malaysia
4Harvard School of Dental Medicine, Harvard University, Boston, MA, USA
5Melbourne Dental School, The University of Melbourne, Carlton, Melbourne, VIC, Australia
6Professor of Oral Pathology, School of Dentistry, University of Athens, Athens Greece
Oral Cancer and Oral Potentially Malignant Disorders
Description
Oral cancer is the sixth most common cancer worldwide. Oral squamous cell carcinoma (OSCC) is characterised by malignancy of the squamous epithelium, which occurs largely in the fifth and sixth decades of life and amongst high tobacco and alcohol consumers. Prognosis is poor, with five-year survival rates reportedly under 50%.
Potentially malignant oral disorders (PMODs) encompass any clinical oral lesion, condition, or disorder which may increase the risk of oral malignancy. PMODs most commonly present as clinical lesions, such as leukoplakia or erythroplakia. Such lesions may or may not exhibit oral epithelial dysplasia (OED) histopathologically; however those which do are considered to be at higher risk of developing into OSCC. Malignant transformation rates of PMODs exhibiting OED have been reported between 5% and 36% over follow-up periods of up to 30 years.
This special issue aims to bring together review articles, original cutting-edge research, and perspective commentary on PMOD and OSCC from a wide range of leading clinicians and researchers in the fields of oral medicine, oral pathology, oral surgery, oral oncology, and beyond. Contributions should be forward-looking and thought-provoking in order to shape future research and clinical practice and drive the development of collaborative evidence-based translational inquiry in this area.
The purpose of this special issue is to offer perspective and stimulate discussion into future-looking concepts on potential topics. Potential topics include, but are not limited to:
- Terminology
- Epidemiology
- Etiology and risk factors
- Clinical and histopathological characteristics
- Diagnostic screening and imaging
- Molecular biomarkers
- Saliva-based diagnostics
- Prevention
- Management and treatment
Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijd/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ijd/ocmd/ according to the following timetable: