TY - JOUR A2 - Agarwal, Anil K. AU - Luisi, Stefano AU - Ciani, Valentina AU - Gabbanini, Massimo AU - Sollazzi, Sofia AU - Torricelli, Michela AU - Calonaci, Francesco AU - Petraglia, Felice PY - 2009 DA - 2009/07/28 TI - Oral Contraceptives after Myomectomy: A Short Term Trial SP - 476897 VL - 2009 AB - Following myomectomy the rate of fertility is restored andpregnancy may be attempted with a good outcome. In the presentstudy a 3 month treatment with OCs in a group of women after amyomectomy was evaluated. The drug compliance and side effects,the benefits of OC in order to reduce symptoms, to increasepost-surgical hemoglobin levels and to avoid an early pregnancyafter myomectomy were analyzed. A group of women (n=55) each with myoma 5 cm was recruited: they presented menorrhagia,pelvic pain, dyspareunia and dysmenorrhae. After laparotomicmyomectomy the women were divided into 3 groups. Group 1: women(n=16) treated with pill A (15 mcg ofethynilestradiol + 60 mcg of gestodene); group 2: women(n=23) treated with pill B (20 mcg ofethynilestradiol + 100 mcg of levonorgestrel); group 3:women (n=16) treated with a placebo (oral calcium). After threemonths from myomectomy and treatment patients in each groupreported a reduced menorrhagia, dismenorrhea and pelvic pain. Serum haemoglobin levels increased in all women (P<.05). No pregnancy occurred in any group and thecompliance was good. A post surgery treatment by using oralcontraceptives guarentees pregnancy prevention, associated withreduction of pain, and improvement of haematologic conditions. SN - 1687-8337 UR - https://doi.org/10.1155/2009/476897 DO - 10.1155/2009/476897 JF - International Journal of Endocrinology PB - Hindawi Publishing Corporation KW - ER -