Prolactin and Male Fertility: The Long and Short Feedback Regulation
Figure 7
Comparative levels of PRL in the serum and CSF of
male rats at different days following castration. Upper panels. Serum PRL
levels. Lower panels. CSF PRL levels. Values are expressed in terms of
NIADDK-rat-PRL-RP-3. “” denotes significant difference at level with respect to
intact controls. Solid line with open circle (--), dashed line with cross (––), and dotted line with closed
circle () represent data from
castrated, intact, and sham operated rats, respectively. At each day of
castration, values are expressed as mean ± SEM of three or more determinations in duplicate of
serum/CSF samples. In intact and sham-operated controls, each value is a mean
of two determinants in duplicate of serum/CSF. Small dots () denote value of each
determination. Vertical bars represent SEM. a, b denote levels of significant difference at or with respect to sham and intact controls. Prolactin was
estimated by RIA in serum and CSF of normal and 1–46 day castrated rats
[66].
