Review Article
Prolactin and Male Fertility: The Long and Short Feedback Regulation
Table 2
Effects of reserpine on prolactin secretion by different pituitary constructs
in response to dopamine agonists and antagonists in vitro.
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Reserpine was dissolved in 25% ascorbic acid and administered s.c to adult male rats for
46 hours. Control group rats received
vehicle alone. Different pituitary constructs were dissected out in DMEM and
incubated at 37°C for 4 hours, in replicates of 10, at each time interval.
Prolactin was assayed in spent medium by
RIA. Values are expressed as mean (ng NIDDK-RAT-PRL-RP-3-ml
incubation medium) ± SEM.
a
significant
difference with respect to 0.05% ascorbic acid ().
b
significant
difference with respect to 25% ascorbic acid control group ().
c
significant difference with respect to PI and PHc of the same group (). *significant difference with respect to PI and P-N of the same
group () [33]. |