Vitamin D Deficiency in Cystic Fibrosis

Table 1

25OH vitamin D levels in CF patients.

Ref	Year	Design	No. of pts	Mean Age	Mean/MEDIAN 25OHD Level
Khazai et al. [29]	2009	RCT	30	32.3	56.8 nmol/l
Fewtrell et al. [30]	2008	observational	32	9.8	63.8
Speeckaert et al. [31]	2008	observational	116	15.1	70.9
Hillman et al. [32]	2008	RCT	15	9.1 +/− 2.3	88.75
Wolfenden et al. [33]	2008	Retrospective Cohort	185	29 ± 9	58.8
Rovner et al. [10]	2007	Prospective case/control	101	14.8 + 4.2	51.7
Gordon et al. [34]	2007	Cross sectional	64	31.4 +/− 9.1	48.4
Stephenson et al. [35]	2007	Retrospective cohort	360	28 +/− 9	47
Boyle et al. [9]	2005	Prospective tx study	134	29.6 +/− 8.9	53.7
Chavasse et al. [36]	2004	Retrospective cohort	290	9 (no SD)	65
Haworth et al. [37]	2004	RCT	30	27.7	57.5
Brown et al. [38]	2003	Case control	10	25.6 +/− 6.5	58.6
Leifke et al. [39]	2003	Cross sectional	40	27.4 +/− 5.4	39.5
Gronowitz et al. [40]	2003	Observational	70	18.8	70.2
Flohr et al. [41]	2002	Observational	75	25.3	69.3
Aris et al. [42]	2002	Case control	50	28.3 +/− 7.8	52.4
Lark et al. [13]	2001	Case control	10	28.9 +/− 8.1	49.4
Elkin et al. [43]	2001	Observational	107	28 +/− 8	38
Grey et al. [44]	2000	Cross sectional	40	10.5 +/− 3.9	74.4
Mortensen et al. [45]	2000	Case control	11	9	55
Conway et al. [46]	2000	Observational	114	24.5	44.9
Haworth et al. [47]	1999	Observational	151	25.3 +/− 7.1	47.4
Aris et al. [48]	1998	Retrospective cohort	70	28.1	52.7
Henderson and Madsen [15]	1996	Observational	54	11.0	64.9
Bhudhikanok et al. [49]	1996	Case control	49	20.6	53% were <44.9
Rochat et al. [16]	1994	Observational	12	23.3	54.9
Grey et al. [50]	1993	Observational	16	23	44.9
Stead et al. [51, 52]	1988	Observational	31	24.5	25.0
Hanly et al. [53]	1985	Observational	20	18	21.3