Increased Daytime Sleepiness in Patients with Childhood Craniopharyngioma and Hypothalamic Tumor Involvement: Review of the Literature and Perspectives
Figure 2
Salivary melatonin concentrations at nighttime (a) and in the morning (b) in patients with childhood craniopharyngioma, hypothalamic pilocytic astrocytoma, and controls in relation to the degree of obesity (body mass index [BMI] <2 SD [filled black boxes], BMI 2–4 SD [hatched gray boxes], or BMI ≥ 4 SD [open boxes]). The horizontal line in the middle of the box depicts the median. Edges of the box mark the 25th and 75th percentile. Whiskers indicate the range of values that fall within 1.5 boxlengths. Values more than 1.5 box-length from the 25th and 75th percentiles are marked by an asterix. (Modified from [5], with the kind permission of Endocrine Press.)
