Chronic Sleep Disturbance Impairs Glucose Homeostasis in Rats

Figure 1

Schematic overview of the sleep disturbance protocols for the restricted sleep group (RS), disturbed sleep group (DS), and control group. For each treatment group, periods of wakefulness induced by forced locomotion are shown in light grey. The RS group was subjected daily to one consolidated block of 20-hour forced activity while the DS group was subjected to blocks of 2-3-hour forced activity interspersed by 3-4-hour blocks of rest. Control animals were left undisturbed.