Research Article
Vitamin D Pathway Genes, Diet, and Risk of Renal Cell Carcinoma
Table 1
General characteristics of genotyped participants.
| | Genotyped participants | |
| Variables | Cases | Controls | |
| | N | % | N | % | † P-value |
| Participants | 777 | 42.9 | 1,035 | 57.1 | | Sex | | | | | | Males | 472 | 60.7 | 648 | 62.6 | | Females | 305 | 39.3 | 387 | 37.4 | .42 | Age at Interview | | | | | | 45 | 60 | 7.7 | 83 | 8.0 | | 45–54 | 197 | 25.4 | 287 | 27.7 | | 55–64 | 243 | 31.3 | 309 | 29.9 | | 65–74 | 242 | 31.1 | 318 | 30.7 | | 75 | 35 | 4.5 | 38 | 3.7 | .30 |
| Mean age (std) | 59.5 years (10.4) | 59.0 years (10.2) | |
| Center | | | | | | Romania-Bucharest | 68 | 8.8 | 94 | 9.1 | | Poland-Lodz | 80 | 10.3 | 189 | 18.3 | | Russia-Moscow | 242 | 31.1 | 313 | 30.2 | | Czech Republic | 387 | 49.8 | 439 | 42.4 | .001 | BMI at Interview | | | | | | 25 | 222 | 28.6 | 375 | 36.3 | | 25–29.9 | 330 | 42.5 | 432 | 41.9 | | 30 | 225 | 29.0 | 225 | 21.8 | .001 | Tobacco status | | | | | | Never | 359 | 46.4 | 420 | 40.7 | | Ever | 415 | 53.6 | 613 | 59.3 | .02 | Hypertension | | | | | | No | 434 | 55.9 | 638 | 61.7 | | Yes | 342 | 44.1 | 396 | 38.3 | .01 | Familial history of cancer Among 1st degree relatives | | | | | | No | 512 | 65.9 | 745 | 72.0 | | Yes | 265 | 34.1 | 290 | 28.0 | .01 |
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Brno, Olomouc, Prague, Ceske-Budejovice; † Crude P-values.
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