The Role of −786T/C Polymorphism in the Endothelial Nitric Oxide Synthase Gene in Males with Clinical and Biochemical Features of the Metabolic Syndrome
Table 3
The comparison of mean values of studied parameters in MS subjects.
Parameter
−786TT
−786TC
−786CC
-value*
−786T
−786C
-value**
Overweight percentage (%)
24.21 ± 11.95
24.14 ± 13.34
25.08 ± 14.9
0.75
24.16 ± 13.02
24.44 ± 13.8
0.98
BMI (kg/m2)
30.6 ± 2.97
30.41 ± 2.93
30.63 ± 2.89
0.91
30.45 ± 2.91
30.46 ± 2.93
0.95
Waist circumference (cm)
101.81 ± 7.73
102.36 ± 7.78
102.53 ± 8.16
0.87
101.93 ± 7.71
102.05 ± 7.84
0.95
Hip circumference (cm)
106.05 ± 6.01
107 ± 5.81
107.05 ± 5.14
0.31
106.7 ± 5.87
107.01 ± 5.66
0.69
Fatty tissue percentage (%)
29.15 ± 5.37
28.81 ± 7.11
29.15 ± 5.37
0.87
28.7 ± 5.86
28.82 ± 5.47
0.69
WHR
0.95 ± 0.04
0.96 ± 0.03
0.97 ± 0.06
0.84
0.95 ± 0.04
0.96 ± 0.05
0.71
Prothrombin index (%)
103.02 ± 6.53
100.7 ± 8.48
99.44 ± 8.93
0.35
101.17 ± 8.15
100.3 ± 8.61
0.62
INR
1.25 ± 1.45
0.99 ± 0.08
0.97 ± 0.06
0.31
1.07 ± 0.82
0.99 ± 0.08
0.51
Fibrynogen (g/L)
3.23 ± 0.65
3.41 ± 0.58
3.56 ± 0.48
0.19
3.37 ± 0.59
3.46 ± 0.55
0.46
CHOLT (mmol/L)
5.44 ± 0.85
5.47 ± 0.98
5.78 ± 0.94
0.04
5.67 ± 0.92
5.72 ± 0.95
0.58
LDL (mmol/L)
3.30 ± 0.82
3.34 ± 0.82
3.52 ± 0.94
0.11
3.45 ± 0.91
3.49 ± 0.92
0.64
HDL (mmol/L)
1.32 ± 0.27
1.29 ± 0.36
1.28 ± 0.28
0.6
1.31 ± 0.27
1.32 ± 0.29
0.76
TG (mmol/L)
1.83 ± 0.59
2.19 ± 1.2
2.47 ± 1.47
0.19
2.34 ± 1.36
2.37 ± 1.39
0.78
Uric acid (μmol/L)
361.72 ± 69.2
368.09 ± 64.7
381.73 ± 63.26
0.19
362.99 ± 68.09
368.08 ± 67.78
0.52
CRP (mg/L)
2.75 ± 2.12
2.77 ± 2.64
3.36 ± 2.98
0.86
2.91 ± 3.01
2.95 ± 3.22
0.91
TSH (mU/L)
1.52 ± 1.21
1.53 ± 0.75
1.67 ± 0.88
0.21
1.52 ± 1.08
1.55 ± 1.15
0.92
Testosterone (pg/mL)
4.64 ± 1.51
4.1 ± 1.3
4.05 ± 1.4
0.28
4.08 ± 1.33
4.21 ± 1.36
0.54
Leptin (ng/mL)
9.11 ± 4.51
9.61 ± 6.21
10.39 ± 4.85
0.46
9.45 ± 5.71
9.76 ± 5.95
0.69
Adiponectin (μg/mL)
7.28 ± 4.12
7.23 ± 3.54
6.14 ± 2.95
0.23
7.24 ± 3.65
6.88 ± 3.39
0.68
Right IMT (mm)
0.54 ± 0.11
0.58 ± 0.15
0.65 ± 0.23
0.02
0.57 ± 0.14
0.6 ± 0.18
0.15
Left IMT (mm)
0.56 ± 0.12
0.57 ± 0.13
0.65 ± 0.2
0.04
0.56 ± 0.12
0.59 ± 0.16
0.29
HOMA-IR
3.35 ± 2.27
3.48 ± 1.56
3.63 ± 2.4
0.50
3.37 ± 2.15
3.44 ± 2.31
0.78
QUICKI
0.74 ± 0.5
0.65 ± 0.28
0.55 ± 0.16
0.07
0.71 ± 0.44
0.69 ± 0.45
0.97
Results expressed as mean values ± SD. Abbreviations: BMI: body mass index. WHR: waist-to-hip ratio. INR: International Normalized Ratio. CHOLT: total cholesterol level. LDL: low density lipoproteins. HDL: high density lipoproteins. TG: triglycerides. CRP: C-reactive protein. TSH: thyrotropin. IMT: intima-media thickness of carotid arteries. HOMA-IR: Homeostasis Model of Assessment-Insulin Resistance. QUICKI: Quantitative Insulin-Sensitivity Check Index.
*
-value refers to the Kruskal-Wallis test and **-value refers to the Mann-Whitney test.
