Hypertension Secondary to PHPT: Cause or Coincidence?

Table 2

Blood pressure, pressor hormones, cytosolic calcium and cardiovascular reactivity to norepinephrine in PHPT patients and age and sex matched normotensive subjects.

	Group 1	Group 2	Group 3	Group 4
Blood pressure, mmHg	171/111 ± 10/8*	118/70 ± 4/3	135/85 ± 3/2	120/70 ± 4/3
Plasma Renin activity ng/mL/h	1.6 ± 0.2*	1.5 ± 0.1	1.3 ± 0.3	1.4 ± 0.2
Plasma aldosterone ng/100 mL	5.2 ± 1.1*	4.5 ± 0.9	4.7 ± 0.9	4.2 ± 1.1
Plasma norepinephrine ng/100 mL	28 ± 3*	24 ± 2	25 ± 3	24 ± 2
Platelet calcium nMol/L	161 ± 18*	105 ± 12	135 ± 12*	112 ± 15
Norepinephrine pressor dose ng/kg/min	95 ± 13*	Not done	115 ± 12*	132 ± 15

* 𝑃<0.05 versus control subjects.
Group 1 hypercalcaemic, hypertensive patients with PHPT.
Group 2 hypercalcaemic, normotensive patients with PHPT.
Group 2 normocalcaemic, pre-hypertensive patients with PHPT.
Group 2 normal subjects.