Microarchitecture, but Not Bone Mechanical Properties, Is Rescued with Growth Hormone Treatment in a Mouse Model of Growth Hormone Deficiency

<table>Finite element models. (a) Femur, positioned with condyles down, loaded in pure bending to an angle of 0.01 radians. (b) Cubes of trabecular bone extracted from the distal region of the L4 vertebral body. On the left, bone from the GH-sufficient mouse and, on the right, bone from a GH-deficient mouse are pictured, each with the median apparent modulus in their respective groups. (c) Vertebrae with endcaps digitally encasing the vertebral body endplates. Vertebrae were loaded in compression to 1% strain.</table>

International Journal of Endocrinology

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Figure 1

Figure 1: Microarchitecture, but Not Bone Mechanical Properties, Is Rescued with Growth Hormone Treatment in a Mouse Model of Growth Hormone Deficiency 

Figure 1 | Microarchitecture, but Not Bone Mechanical Properties, Is Rescued with Growth Hormone Treatment in a Mouse Model of Growth Hormone Deficiency 