Surgery and Radiosurgery for Acromegaly: A Review of Indications, Operative Techniques, Outcomes, and Complications

Table 2

Radiosurgery case series including greater than 50 acromegalic patients.

	Number of Patients	Type of radiosurgery	Mean marginal dose (Gy)	Acromegaly remission (%)	Mean followup (months)	Pituitary hormone deficiency (%)
Losa et al. 2008 [30]	83	GK	25 (goal)	60.2	69	8.5
Jagannathan et al. 2008 [26]	95	GK	22	53	57	34
Vik-Mo et al. 2007 [31]	61	GK	26.5	17	66	13
Voges et al.2006 [32]	64	LINAC	15.3*	37.5	81.9*	12.3*
Jezkova 2006 [33]	96	GK	32	44	53.7	27
Castinetti et al. 2005 [34]	82	GK	26.3	17	49.5	17
Kobayashi et al. 2005 [35]	67	GK	18.9	16.7	63.3	14.6
Jane et al. 2003 [36]	64	GK	15*	36	NR	28
Zhang et al. 2000 [37]	68	GK	31.3	96	>24	NR

*represents all adenomas in study not specific to growth hormone pituitary adenomas.
NR = value not recorded in study.