Review Article

Muscular Dystrophies at Different Ages: Metabolic and Endocrine Alterations

Figure 1

Histology of necrotic skeletal muscle. Image (a) showed a normal skeletal muscle from quadriceps muscle, characterized by healthy myofibres with peripheral nuclei (PN). Skeletal muscle of control subjects was obtained from males without dystrophinopathies at 40 years old. Image (b) showed a necrotic skeletal muscle from quadriceps muscle of a patient with DMD/DMB at five years old, characterized by infiltrating inflammatory cells (ICs) and degenerating myofibres (DMs). Transverse muscle sections stained with haematoxylin and eosin. Scale bar represents 50 m. This biopsy was obtained for the purpose of performing diagnostic.
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(a)
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